The Probability of Finding a Suitable Related Donor for Bone Marrow Transplantation in Extended Families

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In bone marrow transplantation, the advantages of family donors over unrelated donors are threefold. (1) Family donors are better matched because they share complete haplotypes. (2) The time between the start of the search and the actual transplantation can be much shorter than for unrelated donors. (3) Related bone marrow transplantation is cheaper. We developed a procedure for calculating the probability of finding a suitable donor among cousins and bloodrelated aunts and uncles (the extended family). The procedure calculates the following probabilities ( P ) : (I) Pthat any blood-related uncle or aunt is a suitable donor, (2) P that a suitable donor exists in all blood-related uncles/aunts (from

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The probability of finding a suitable related donor for bone marrow transplantation in extended families.

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تاریخ انتشار 2002